Melagenin Plus
A Cuban-developed topical medication from human placental extract that stimulates melanocyte activity to help restore skin color in vitiligo.
Melagenin Plus
A Cuban-developed topical medication from human placental extract that stimulates melanocyte activity to help restore skin color in vitiligo.
Melagenin Plus at a glance
Melagenin Plus is a topical (applied to the skin) medication developed in Cuba from human placental extract. It is designed to stimulate melanocytes — the cells that produce melanin, the pigment that gives skin its color — in areas affected by vitiligo. It is one of Cuba's distinctive dermatological treatments, attracting patients from around the world who are looking for repigmentation (color restoration) options.
How It Works
Melagenin Plus contains factors derived from human placental extract that are designed to stimulate melanocyte activity — the cells responsible for producing melanin. In vitiligo, melanocytes are destroyed or stop functioning, causing white patches on the skin. Melagenin Plus is applied to the depigmented (white) areas, followed by brief, controlled sun exposure or phototherapy (light therapy), which together aim to stimulate repigmentation of the affected skin.
Treatment Protocol
Melagenin Plus is applied to the white patches of skin, followed by brief, controlled sun exposure or phototherapy sessions. Treatment is given on an outpatient basis at Cuban dermatology facilities. Patients receive the medication and detailed instructions for use, often combining in-clinic sessions with a take-home treatment plan. The initial in-clinic phase typically lasts 2–4 weeks, followed by continued take-home treatment for several months.
Conditions Treated
Clinical Evidence
Melagenin Plus was developed at Cuba's Placental Histotherapy Center in Havana. It has been used to treat vitiligo patients from around the world. Results vary depending on how widespread and how long-standing the depigmentation is. Treatment works best on newer patches and certain body areas. Patients with widespread or long-standing vitiligo may still benefit but should have realistic expectations.
Availability
Melagenin Plus is a Cuban-developed product available through SMC Salud's international patient services. Patients travel to Cuba to begin treatment, which can then be continued at home with take-home medication. A dermatological evaluation determines individual suitability.
Frequently Asked Questions
Related Information
Medically Reviewed
SMC Salud Medical Review Board
Board-certified physicians and specialists in oncology, neurology, dermatology, and endocrinology
Last reviewed: January 15, 2025
This content has been medically reviewed by qualified physicians and follows SMC Salud's editorial policy for health information. Medical content is for informational purposes and does not replace professional medical advice.
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Treatment suitability depends on specialist evaluation. Individual treatment plans apply.