
Vitiligo Treatment with Melagenin Plus: What Patients Should Know
By the SMC Salud Medical Editorial Team
Understanding Cuba's placental extract-based therapy for vitiligo — how it works, treatment protocols, expected timelines, and realistic expectations for repigmentation.
Melagenin Plus is a topical (applied to the skin) medication developed in Cuba from human placental extract. It is designed to stimulate melanocytes — the cells that produce melanin, the pigment that gives skin its color — in areas affected by vitiligo. It is one of Cuba's distinctive dermatological treatments, attracting patients from around the world who are looking for repigmentation (color restoration) options.
Melagenin Plus is applied to the white patches of skin, followed by brief, controlled sun exposure or phototherapy (light therapy) sessions. It is given on an outpatient basis at Cuban dermatology facilities, and patients receive the medication with detailed application instructions, often combining in-clinic sessions with a take-home treatment plan.
Repigmentation is a gradual process. You may see initial results after several weeks, with continued improvement over months. Treatment works best on newer patches and certain body areas. Patients with widespread or long-standing vitiligo should have realistic expectations. A dermatological evaluation determines individual suitability and treatment duration, which typically lasts 3-5 weeks in Cuba.
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